To verify therapeutic range for diazepam you are a real person, DoveMed requires each survey to be answered while logged in. The laboratory test results are NOT to be interpreted as results of a "stand-alone" test. Your healthcare providers will explain the meaning of your therapeutic range for diazepam results, based on the overall clinical scenario. Certain medications that you may be currently taking may influence the outcome of the test.

By intramuscular injection, or by slow intravenous injection. By intravenous infusion, or by therapeutic range for diazepam tube. With rectal use in children. Benzodiazepines should only be administered therapeutic range for diazepam anaesthesia by, or under the direct supervision of, personnel experienced in their use, with adequate training in anaesthesia and airway management. Avoid injections containing benzyl alcohol in neonates ; chronic psychosis in adults ; CNS depression ; compromised airway ; hyperkinesis ; not for use alone to treat depression or anxiety associated with depression in adults ; obsessional states ; phobic states ; respiratory depression.

Send the page " " to a friend, relative, colleague or yourself. We do not record any personal information entered above. As with other benzodiazepines, diazepam should be used with caution in patients with pulmonary disease. Additionally, avoid coadministration with other CNS depressants, especially opioids, unless no other alternatives are available as coadministration significantly increases the risk for respiratory depression, low blood pressure, and death. Oral diazepam tablets are contraindicated for use in those with severe respiratory insufficiency or sleep apnea syndrome.

Diazepam, a benzodiazepine derivative, is an anxiolytic agent that reduces neuronal depolarization resulting in decreased action potentials. It enhances the action of gamma-amino butyric acid GABA by tightly binding to A-type GABA receptors, thus opening the membrane channels and allowing the entry of chloride ions. It is also used as a muscle relaxant, procedural sedation agent, and sedative-hypnotic agent to treat withdrawal states ie, ethanol , along with other conditions seizures. Diazepam is metabolized to several metabolites in the liver including temazepam, oxazepam, and nordiazepam desmethyldiazepam and the clearance of the drug is reduced considerably in the elderly and in patients with hepatic disease.

Total serum benzodiazepine concentrations were correlated with clinical manifestations in 93 cases of diazepam overdose. Diazepam and nordiazepam were also each separately determined in serum specimens from cases of diazepam overdose, including 27 cases from the aforementioned clinical correlation study. In addition, serum nordiazepam concentrations were measured in five cases of clorazepate overdose. All patients survived with supportive therapy only. Each of the 25 patients who had ingested only diazepam was awake or in grade 0 coma, even when drug concentrations were ten-fold greater than the accepted upper limit of the therapeutic range. None of the patients who had ingested only diazepam needed hospitalization; all were discharged from acute medical care after a period of emergency room observation. The ratios of parent drug to N-desmethyl metabolite nordiazepam in those overdose specimens analyzed by gas chromatography averaged 3:

therapeutic range for diazepam

Medically reviewed therapeutic range for diazepam December 12, Moderate Anxiety Disorders and Symptoms: Management of anxiety disorders and short-term relief of anxiety symptoms. Larger parenteral doses may be necessary for patients with tetanus. Adjunctive treatment for the relief of skeletal muscle spasm due to reflex spasm to local pathology, spasticity caused by upper motor neuron disorders, athetosis, and stiff-man syndrome e. Usually less than 10 mg, but some patients require up to 20 mg IV, especially when narcotics are therapeutic range for diazepam -IV titration: The IV dose should be titrated to desired sedative response e.

Medically reviewed on December 12, Moderate Anxiety Disorders and Symptoms: For diazepam of anxiety disorders and short-term relief of anxiety symptoms. Larger parenteral doses may be necessary for patients with tetanus. Adjunctive treatment for the therapeutic range of skeletal muscle spasm due to reflex spasm to local pathology, spasticity caused by upper motor therapeutic range for diazepam disorders, athetosis, and stiff-man syndrome e. Usually less than 10 mg, but some patients require up to 20 mg IV, especially when narcotics are omitted -IV titration: The IV dose should be titrated to desired valium to help stop smoking response e. Adjunct to status epilepticus and severe recurrent convulsive for diazepam. Premedication for the relief of anxiety and tension in patients undergoing surgical procedures.

By intramuscular injection, or by slow intravenous injection. By intravenous infusion, or by nasoduodenal tube. With rectal use in children. Benzodiazepines should only be administered for anaesthesia by, or under the direct supervision of, personnel experienced in their use, with adequate training in anaesthesia and airway management. Avoid injections containing benzyl alcohol in neonates ; chronic psychosis in adults ; CNS depression ; compromised airway ; hyperkinesis ; not for use alone to treat depression or anxiety associated with depression in adults valium or xanax for mri anxiety disorder obsessional states ; therapeutic range for diazepam states ; respiratory depression. Muscle weakness ; organic therapeutic range for changes ; parenteral administration close observation required until full recovery from sedation. With intravenous use. When given intravenously facilities for reversing respiratory depression with mechanical ventilation must be immediately available. Diazepam abnormal ; concentration impaired in adults ; muscle spasms ; palpitations ; diazepam for therapeutic range disorder ; vomiting in adults.

Medically reviewed on December 12, Moderate Anxiety Disorders and Symptoms: Management of anxiety disorders and short-term relief of anxiety symptoms.