Ativan lorazepam is a prescription tranquilizing medication. You might also hear it called a sedative-hypnotic or anxiolytic medication. Ativan belongs to a class of medications called benzodiazepines.

same are ativan diazepam and the

This conversion tool estimates a reasonable equipotent dose between two benzodiazepines. Unlike opioid equipotent dosingbenzodiazepine equivalence is much less evidence-based and poorly described in the literature. In fact, most benzodiazepine equivalence estimates are based on expert opinion, uncited tables in published documents, and clinical practice.

All benzodiazepine conversions used in this calculator are based on published phentermine no side effects are diazepam estimates. The following guiding principles govern the calculator's logic:. Due to discrepancies the same the literature, many benzodiazepine conversions may have a potential conversion range that is extremely variable eg, by a factor of 10x or greater. These wide ranges of confidence highlight the lack of firm, evidence-based literature supporting specific conversion ratios.

In addition to an overall lack of evidence to support specific conversions, there are a number of other limitations that should be recognized:. Given the numerous issues with benzodiazepine equivalence, the importance of reasonable clinical judgment, clinical experience, appropriate patient monitoring, and dose titration are of even greater significance. And ativan benzodiazepines included in this calculator are only available as oral dosage forms.

Midazolam, lorazepam, diazepam, and phenobarbital are available in both parenteral and oral formulations. Because published benzodiazepine dose conversions are based on oral administration, parenteral formulations may same use the same conversion ratio. The following bioavailabilities are available based on published literature. Note how the large variances in oral bioavailability highlight the significant inter-patient variability:.

Unlike nearly all other benzodiazepine conversions, the conversion between intravenous midazolam and lorazepam has been well studied in mechanically ventilated patients. It should be noted, however, that this conversion same based on chronic administration of continuous intravenous lorazepam or midazolam. Although phenobarbital and secobarbital are not benzodiazepines, they are commonly grouped with this drug class and cited within benzodiazepine conversion charts due the same their use in are diazepam lorazepam and memory problems. While barbiturates do share similar pharmacology to benzodiazepines, they have a more concerning safety profile with a higher incidence of respiratory depression.

Show Same citation. Press 'Calculate' to view and are diazepam results. Load an Example. This calculator only accounts for diazepam and the same ativan are in bioavailability with midazolam. Management of withdrawal syndromes and relapse prevention in drug and alcohol dependence. Am Fam Physician. PMID Quan D.

Chapter Tintinalli's Emergency Medicine: A Comprehensive Study Guide. New York: McGraw-Hill; Evaluation of an alcohol withdrawal protocol and a preprinted order set at a tertiary care hospital. Can J Hosp Pharm. Dose equivalence of midazolam and triazolam. A psychometric study based on flicker sensitivity, reaction time and digit symbol substitution and ativan the. Eur J Clin Pharmacol.

Lieberman JA, Tasman A. Handbook of Psychiatric Drugs. Ashton H. How they work and how to withdraw; The ativan Ashton Manual. Newcastle, UK; The Ashton Manual Online. Effect of age, gender, and obesity on midazolam kinetics. Pharmacokinetics of midazolam following intravenous and oral administration in patients with chronic liver disease and in healthy subjects. J Clin Pharmacol.

Lorazepam [package insert]. Corona CA: Watson Laboratories; DailyMed Monograph. Bioavailability of diazepam after intravenous, oral and rectal administration in adult epileptic patients. Br How much ambien can i give my dog Clin Pharmacol. Diazepam absorption: Dig Dis Sci. Absolute bioavailability of oral and intramuscular diazepam: Anesth Analg. Phenobarbital pharmacokinetics and bioavailability in adults.

A double-blind, randomized comparison of i. Follow Us! Get Email Updates. Open Menu. Benzodiazepine Equivalents Conversion Calculator. Updated The same 3, Accessed February 17, All rights reserved. Home Academy Blog About. Back to Top.