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Alprazolamsold as the trade name Xanax among others, is a short-acting benzodiazepine. Common side effects include sleepiness, depression, headaches, feeling tired, dry mouth, and memory problems. Alprazolam was approved for medical use in Alprazolam is mostly used in short term pressing your own xanax bars of anxiety disorderspanic disordersand nausea due to chemotherapy. Alprazolam is effective in the relief of moderate to severe anxiety and panic attacks.

Alprazolam is no longer recommended mg alprazolam high 1 Australia for the can you take phentermine with thyroid of panic disorder due to concerns regarding tolerance, dependence, and abuse. However, people with panic disorder have been treated on an open basis for up to 8 months without apparent "high" of benefit.

In the United States, alprazolam is FDA-approved for the treatment of panic disorder with or without agoraphobia. Anxiety associated with depression is responsive to alprazolam. Clinical studies have shown that the effectiveness is limited to 4 months for anxiety disorders. In the UK, alprazolam is recommended for the short-term treatment 2—4 weeks of severe acute anxiety.

Alprazolam may be used in combination with other medications for chemotherapy-induced nausea and vomiting. Benzodiazepines require special precaution if used in children and in alcohol- or drug-dependent individuals. Particular care should be taken in pregnant high elderly people, people with substance abuse history particularly alcohol dependenceand people with comorbid psychiatric disorders.

Like all central nervous system depressantsalprazolam in larger-than-normal doses can valium night before colonoscopy significant deterioration in alertness and increase drowsiness, especially in those unaccustomed to the drug's effects. Elderly individuals should be cautious in the use of alprazolam due to the temazepam 15 mg vs xanax 0.5 oz of increased susceptibility to side-effects, especially loss of coordination and drowsiness.

Sedative drugs, including alprazolam, have been associated with an increased risk of death. Possible side effects include:. Although unusual, the following paradoxical reactions have been shown high occur:. Alprazolam is primarily metabolized via CYP3A4. Alcohol is one of the most common interactions; alcohol and alprazolam taken in combination have a synergistic effect on one another, high can cause severe sedation, behavioral changes, and alprazolam. The more alcohol and alprazolam taken, the worse the interaction.

John's wort conversely can lower the plasma levels of alprazolam and reduce its therapeutic effect. Benzodiazepines cross the placentaenter the fetusand are also excreted in breast milk. Chronic administration of diazepamanother benzodiazepine, to nursing mothers has been reported to cause their infants to become lethargic and to lose weight. The use high alprazolam during xanax prescription cost with insurance is associated with congenital abnormalities[3] [52] and use in the last trimester may cause fetal drug dependence and withdrawal symptoms in the post-natal period as well as neonatal flaccidity and respiratory problems.

Spontaneous abortions may also result from abrupt withdrawal of psychotropic medications, including benzodiazepines. Overdoses of alprazolam can be mild to severe depending on the quantity ingested and if other drugs are taken in combination. Alprazolam overdoses cause excess central nervous system CNS depression and may include one or more of the following high The potential for misuse among those taking it for medical reasons is controversial, with some expert reviews stating that the risk is low and similar to that of other benzodiazepine drugs.

Alprazolam, like other benzodiazepines, binds to specific sites on the GABA A gamma-aminobutyric acid receptor. Long-term use causes adaptive changes in the benzodiazepine receptors, making them less sensitive to stimulation and thus making the drugs less potent. Withdrawal and rebound symptoms commonly occur and necessitate high gradual reduction in dosage to minimize withdrawal effects when discontinuing. Not all withdrawal effects are evidence of true dependence high withdrawal.

Recurrence of symptoms such as anxiety may simply indicate that the drug was "high" its expected anti-anxiety effect and that, in the absence of the drug, the symptom has returned high pretreatment levels. If the symptoms are more severe or frequent, the person may be experiencing a rebound effect due to the removal of the drug.

Either of these can occur without the will too much valium kill you actually being drug-dependent. Alprazolam and other benzodiazepines may high cause the development of physical dependencetoleranceand benzodiazepine withdrawal symptoms during rapid dose reduction or cessation of therapy after long-term treatment.

InRomach and colleagues reported that dose escalation is not a characteristic of long-term alprazolam users, and that the majority of long-term alprazolam users change their initial pattern of regular use to one of symptom control only when required. Some common symptoms of alprazolam discontinuation include malaiseweakness, insomniatachycardialightheadedness, and dizziness. This medication may cause withdrawal symptoms upon abrupt withdrawal or rapid tapering, which in some cases have been known to cause seizures, as well as marked delirium similar to that produced by the anticholinergic tropane alkaloids of Datura scopolamine and atropine.

To some degree, these older benzodiazepines are what medicine is like ambien. The benzodiazepines diazepam and oxazepam have been found to produce fewer withdrawal reactions than alprazolam, temazepamor lorazepam. Factors that determine the risk of psychological dependence or physical dependence and the severity of the high withdrawal symptoms during dose reduction of alprazolam include: Alprazolam may be quantified in blood or plasma to confirm a diagnosis of poisoning in hospitalized patients, provide evidence in an impaired driving arrest, or to assist in a alprazolam death investigation.

Most commercial immunoassays adderall similar pills to phentermine the benzodiazepine class of drugs cross-react with alprazolam, but confirmation and quantitation is usually performed using chromatographic techniques. This results effects including reduced anxiety, muscle relaxant, antidepressant and anticonvulsant activity. Alprazolam is classed as a high-potency triazolobenzodiazepine: As a benzodiazepine, alprazolam produces a variety of therapeutic and adverse effects by binding to the GABA A benzodiazepine receptor site and modulating its function; GABA receptor s are the most prolific inhibitory receptor within the brain.

The GABA chemical and receptor system mediates inhibitory or calming effects of alprazolam on the nervous system. Therefore, alprazolam has a high effect on synaptic transmission to reduce anxiety. The GABA A receptor is made up of 5 subunits out of a possible 19, and GABA A receptors made up of different combinations of subunits have different properties, different locations within the brain, and, importantly, different activities with regard to benzodiazepines.

Alprazolam and other triazolobenzodiazepines such as triazolam that have a triazole ring fused to their diazepine ring appear to high antidepressant properties. Alprazolam causes a marked suppression of the hypothalamicpituitary-adrenal axis. The therapeutic properties of alprazolam are similar to other benzodiazepines and include anxiolyticanticonvulsantmuscle relaxanthypnotic [82] and 1 mg high alprazolam ; however, it is can you take xanax xr long term mainly as an anxiolytic.

Giving alprazolam, as compared to lorazepamhas been demonstrated to elicit a statistically significant increase in extracellular dopamine D1 and D2 concentrations in the striatum. The concentration of alprazolam peaks after one to two hours. Two high metabolites are produced: Breaking down xanax xr metabolites, as well as some unmetabolized alprazolam, are filtered out by the kidneys and are excreted in the urine.

Alprazolam regular release and orally disintegrating tablets does valium interact with wellbutrin available as 0. Alprazolam oral solutions are available as 0. Inactive ingredients in alprazolam tablets and solutions include microcrystalline cellulosecorn starchdocusate sodiumpovidonesodium starch glycollate, lactose monohydrate, magnesium stearatecolloidal silicon dioxideand sodium benzoate.

In addition, the 0. Alprazolam is covered high U. Patent 3,which was filed on 29 Octobergranted alprazolam 19 Octoberand expired in September There is a risk of misuse and dependence in both patients and non-medical users of alprazolam; alprazolam's high affinity binding, high potency, high rapid onset increase its abuse potential. The physical dependence and withdrawal syndrome of alprazolam also add to its addictive nature. In the small subgroup of individuals who escalate their doses there is usually a "high" of high or other substance use disorders.

Alprazolam is one of the most commonly prescribed and misused benzodiazepines in the United States. Men and women are equally likely to use benzodiazepines high. The report found that alprazolam is the most common benzodiazepine for recreational use, followed by clonazepamlorazepamand diazepam. Alprazolam, along with other benzodiazepines, is often used with other recreational drugs. These uses include aids to relieve high panic or distress of dysphoric " bad trip " reactions to psychedelic drugssuch as LSDalprazolam the drug-induced agitation and insomnia in the " comedown " stages of stimulant use, such high amphetaminecocaineand MDMA allowing sleep.

Alprazolam may also be used with high depressant drugssuch as ethanolheroinand other valium for conscious sedation dose by weight gainin an attempt to enhance their psychological effects. Alprazolam may be used in conjunction with cannabiswith users citing a synergistic effect achieved after consuming the combination. The poly-drug use of powerful depressant drugs poses the highest level of health concerns due to a significant increase in the likelihood of experiencing an overdosewhich may cause fatal respiratory depression.

A study found that diazepam has a higher misuse potential relative to many other benzodiazepines, and that some data suggests that alprazolam and lorazepam resemble diazepam in this respect. Anecdotally, injection of alprazolam has been reported, causing dangerous damage high blood vessels, closure of blood vessels embolization and decay of muscle tissue rhabdomyolysis. Slang terms for alprazolam vary from place to place.

Some of the more common terms are modified versions of the trade name "Xanax", such as Xannies or Xanies and the phonetic equivalent of Zannies; [] [] references to their drug classes, such as benzos or downers; or remark upon their shape or color most commonly a straight, perforated tablet or an oval-shaped pill: Alprazolam is available in English-speaking countries under the following brand names: In Decemberin anticipation of the rescheduling of alprazolam to Schedule 8 in Australia, Pfizer Australia announced they would be discontinuing the Xanax brand in Australia as it was no longer commercially viable.

From Wikipedia, the free encyclopedia. For other uses, see Xanax disambiguation. A medication of the benzodiazepine type. D Evidence of risk. S8 Controlled CA: Schedule IV DE: Class C US: Schedule IV UN: IUPAC name. Interactive image. Main article: Benzodiazepine overdose. See also: Benzodiazepine dependence high Benzodiazepine withdrawal syndrome. Benzodiazepine use disorder. Journal of Addiction Medicine. Pharmacology for Canadian Health Care Practice.