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Tramadol is one of the most potent analgesics available today to treat moderately severe pain; however, like all pharmacological medications, tramadol is also harmful in large doses or even in normal dosage in some genetically susceptible individuals. Analgesics are the "does tramadol make you itchy" pain medications that we all consume for different types of aches and pains. Common over-the-counter pain medications such as Aspirin and Tylenol are classified as NSAIDs Non-steroidal anti-inflammatory drugs and can treat most trivial muscular pains.