dose tramadol minimum effective

Management tramadol minimum effective dose xanax and urinary frequency severe enough to require an opioid analgesic and for which alternative treatments are inadequate. Use lowest effective dose for tramadol minimum effective dose duration. Renal impairment CrCl Children Addiction, abuse, and misuse. Ultra-rapid metabolism of tramadol and other risk factors for life-threatening respiratory depression in children.

Neonatal opioid neck pain and xanax withdrawal threads syndrome. Risks from concomitant use with benzodiazepines or other CNS depressants. Life-threatening respiratory depression; monitor within first 24—72hrs of initiating therapy and following dose increases. Accidental exposure may cause fatal overdose esp. Risk of life-threatening respiratory depression and death related to ultra-rapid metabolizers of tramadol esp.

Avoid in adolescents 12—18yrs with conditions associated with hypoventilation eg, post-op status, obstructive sleep apnea, obesity, severe pulmonary disease, neuromuscular disease, concomitant drugs that cause respiratory depression. COPD, cor pulmonale, decreased respiratory reserve, hypoxia, hypercapnia, or pre-existing respiratory depression; monitor and consider non-opioid analgesics.

Increased intracranial pressure, brain tumors; monitor. Avoid in depressed, suicidal, or addiction-prone patients; consider non-narcotic analgesics. Impaired consciousness, coma, shock; avoid. Pregnancy; potential neonatal opioid tramadol minimum effective dose syndrome during dose tramadol minimum effective use.

Concomitant other forms of tramadol or carbamazepine: May be affected by CYP2D6 inhibitors eg, amiodarone, quinidine, fluoxetine, paroxetine, bupropion. Potentiated by CYP3A4 inhibitors eg, macrolides, azole antifungals, protease inhibitors. Antagonized by CYP3A4 inducers eg, rifampin, carbamazepine, phenytoin. May antagonize diuretics; monitor. Paralytic ileus may occur with anticholinergics.

Dizziness, nausea, constipation, headache, somnolence, flushing, pruritus, vomiting, insomnia, dry mouth; respiratory depression, severe hypotension, syncope; rare: Generic Name and Formulations: Tramadol HCl 50mg; scored tabs. Renal impairment CrCl Children: Addiction, abuse, and misuse. Formerly known under the brand name Ultram ER.

ER tabs—contact supplier; Tabs—